New to GLP-1 medications? Let’s break down the basics.
What Are GLP-1s?
GLP-1 (glucagon-like peptide-1) receptor agonists are medications that mimic a natural hormone. They were originally developed for type 2 diabetes but have shown significant weight loss benefits.
FDA-Approved Options
Currently approved GLP-1 medications include:
Semaglutide
- Ozempic - Diabetes (weekly injection)
- Wegovy - Weight management (weekly injection)
- Rybelsus - Diabetes (daily oral)
Tirzepatide
- Mounjaro - Diabetes (weekly injection)
- Zepbound - Weight management (weekly injection)
Liraglutide
- Victoza - Diabetes (daily injection)
- Saxenda - Weight management (daily injection)
For official prescribing information: FDA Drug Database
How They Work
- Slow gastric emptying - Food stays in stomach longer
- Reduce appetite - Signal brain to feel full
- Improve insulin response - Better blood sugar control
- Reduce glucagon - Less glucose release from liver
Common Side Effects
Most people experience some of these, especially starting out:
- Nausea
- Decreased appetite
- Constipation or diarrhea
- Stomach discomfort
These often improve with titration and time.
Important Considerations
- Requires prescription and medical supervision
- Not for everyone (contraindications exist)
- Part of comprehensive weight management approach
- Results vary by individual
Questions? Ask below!
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